PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics | Oncogene
PROTAC-mediated ternary complex formation and hook effect. The hook... | Download Scientific Diagram
Frontiers | From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
Proteolysis‐targeting chimeras in drug development: A safety perspective - Moreau - 2020 - British Journal of Pharmacology - Wiley Online Library
Proteolysis‐targeting chimeras in drug development: A safety perspective - Moreau - 2020 - British Journal of Pharmacology - Wiley Online Library
Pharmaceutics | Free Full-Text | Estrogen Receptor-α Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs
Target and tissue selectivity of PROTAC degraders - Chemical Society Reviews (RSC Publishing) DOI:10.1039/D2CS00200K
Current strategies for the design of PROTAC linkers: a critical review
Characterizing PROTAC ternary complex formation using Biacore SPR systems | Cytiva
Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation | Nature Communications
Pharmaceutics | Free Full-Text | A Mechanistic Pharmacodynamic Modeling Framework for the Assessment and Optimization of Proteolysis Targeting Chimeras (PROTACs)
a) PROTAC-mediated ternary complex formation and Hook effect as a... | Download Scientific Diagram
Hypoxia deactivates epigenetic feedbacks via enzyme-derived clicking proteolysis-targeting chimeras | Science Advances
Frontiers | From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
A suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by
Current strategies for improving limitations of proteolysis targeting chimeras
Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs - ScienceDirect
Frontiers | From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
An AURKA PROTAC cocktail relieves the hook effect. A) Scheme depicting... | Download Scientific Diagram
The Development and Application of Biophysical Assays for Evaluating Ternary Complex Formation Induced by Proteolysis Targeting Chimeras (PROTACS) | Protocol
PROTACs: Current Trends in Protein Degradation by Proteolysis-Targeting Chimeras | BioDrugs
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
Mechanistic and Structural Features of PROTAC Ternary Complexes | SpringerLink
Design, synthesis, and biological evaluation of small molecule PROTACs for potential anticancer effects | Medicinal Chemistry Research
Biomolecules | Free Full-Text | Central Nervous System Targeted Protein Degraders
PROTAC-mediated ternary complex formation and hook effect. The hook... | Download Scientific Diagram
Protein Degraders | Targeted Protein Degradation | Bio-Techne
